Sanaphorce 123: Supporting Feed Hygiene and Gut Health in Poultry

Maintaining a balanced gut microbiota is essential for stable poultry performance. Pathogenic bacteria such as Escherichia coli and Salmonella are a constant challenge in modern poultry production and can negatively affect animal health, litter quality, and production efficiency. Sanaphorce 123 is a practical nutritional tool developed by NuSana to support feed hygiene, gut health, and performance in poultry.

Pathogenic Pressure in Poultry Production

Enterobacteriaceae, including E. coli and Salmonella, are widely present in poultry systems. At high levels they may cause clinical symptoms such as wet litter and dirty eggs, while at lower levels they often lead to sub‑clinical performance losses. These effects can remain unnoticed but still reduce growth and efficiency.

Young chicks are particularly vulnerable. Due to lower hydrochloric acid (HCl) secretion, stomach pH remains relatively high in early life, which limits pepsin activity and reduces protein digestion. Undigested protein entering the intestine can promote E. coli overgrowth and increase pathogenic pressure.

Supporting a Healthy Gut Environment

A healthy gut microbiota can be supported through targeted nutritional strategies, including:

• Reducing pathogenic load in the feed

• Supporting a low stomach pH as a natural barrier function

• Reducing pathogenic pressure in the crop, stomach, and intestines

Sanaphorce 123 was developed to support these mechanisms in a practical and controlled way.

What Is Sanaphorce 123?

Sanaphorce 123 is an organic acid–based poultry product that is active in the feed and throughout the gastrointestinal tract. According to NuSana documentation, the product:

• Improves feed hygienic quality

• Helps reduce Salmonella, coliforms, and other Enterobacteriaceae

• Supports acidification to reach a low stomach pH, contributing to natural pathogen defence and improved protein digestion

• Exerts antibacterial activity in the crop, stomach, and intestines

These combined actions aim to reduce pathogenic pressure and support stable poultry performance.

Mode of Action: Organic Acids and Essential Oils

Organic acids act by penetrating bacterial cell walls in their undissociated form. Once inside the cell, they dissociate, releasing hydrogen ions (H⁺) that disrupt cellular energy balance while acid anions interfere with bacterial DNA function. This mechanism is particularly effective under low pH conditions.

Sanaphorce 123 also benefits from the documented synergistic effect between organic acids and essential oil components such as cinnamaldehyde. Research data included in NuSana materials show that this combination enhances antibacterial efficacy against E. coli and Salmonella compared with acids or essential oils alone.

Performance Results in Poultry

NuSana technical data include both commercial and institute‑based evaluations of Sanaphorce 123:

• Commercial comparison with a competing acidifier showed a higher average daily weight gain (+3.7%), slightly earlier slaughter age, and lower feed cost per kg gain when Sanaphorce 123 was used.

• Institute trial (Feed Innovation Services, NL, 2024) with Ross 308 broilers demonstrated:

  • Lower feed conversion ratio (FCR)

  • Improved European Production Efficiency Factor (EPEF)

  • Reduced feed cost per kg meat

The trial was conducted under controlled research conditions, with the note that performance responses are often larger under practical field conditions.

Targeting Salmonella

Laboratory growth medium tests presented in NuSana materials show that Sanaphorce 123 can significantly reduce Salmonella growth, with more than 75% reduction observed at specific inclusion levels, depending on the Salmonella strain.

A Practical Tool for Poultry Nutrition

Sanaphorce 123 fits within NuSana’s approach of providing science‑based, performance‑oriented feed solutions. By combining organic acids with selected functional components, the product supports feed hygiene, gut health, and production efficiency without relying on claims beyond documented mechanisms and results.

Would you like to learn more about Sanaphorce 123?

Sanaphorce 123 is part of NuSana’s science‑based approach to improving feed hygiene, gut health, and poultry performance under practical conditions.

If you would like to:

• Discuss how Sanaphorce 123 fits into your current poultry feeding strategy

• Receive technical guidance or trial data relevant to your market

• Explore tailored solutions for your production challenges

Get in touch with the NuSana team.
We are happy to support you with practical advice and reliable nutritional solutions.

👉 Contact NuSana
👉 Speak with one of our technical specialists