Butiphorce 1065: Supporting Gut Integrity and Performance in Poultry and Swine
A well‑functioning intestinal epithelium is a key foundation for animal performance. The gut is responsible not only for digestion and nutrient absorption, but also plays a central role in immune function and overall resilience. Butiphorce 1065 is NuSana’s advanced solution designed to support gut health and performance in poultry and swine through a targeted supply of butyric acid.

Edwin van Kol
Gut Health

Why Gut Integrity Matters
The intestinal epithelium acts as a physical and functional barrier between the animal and its environment. Damage to this barrier can lead to inflammation, reduced nutrient uptake, and increased susceptibility to pathogens. Scientific literature consistently shows that butyric acid plays an important role in supporting gut morphology, epithelial integrity, and feed efficiency.
By supporting the structure and function of the gut wall, nutrition can contribute to better growth rates, improved feed conversion ratio (FCR), and more stable animal performance under commercial conditions.
What Is Butiphorce 1065?
Butiphorce 1065 is a latest‑generation, slow‑release butyric acid product developed by NuSana. It is based on butyric acid glycerides (tributyrin) and contains 50% butyric acid, with targeted release in the intestines and no odour issues during handling or feed processing.
Compared with unprotected or salt forms of butyric acid, Butiphorce 1065 is designed to ensure that butyrate becomes available where it is most effective: in the intestinal tract.
Mode of Action: From Gut Cells to Performance
Butyric acid is an important energy source for intestinal epithelial cells. Research highlighted in NuSana materials shows that butyrate supports:
Mucus production and antimicrobial proteins
Integrity of intestinal epithelial cells and tight junctions
Regulation of inflammatory responses
Activation of regulatory T‑lymphocytes and oral tolerance
These effects contribute to a healthier and more resilient gut environment.
In addition, butyrate interacts with L‑cells in the gut epithelium, stimulating the release of hormones such as GLP‑1 and GLP‑2. GLP‑2 is known for its intestinotrophic effects, supporting epithelial regeneration, nutrient uptake, and gut integrity.
Documented Benefits in Poultry and Swine
Data presented in NuSana technical materials demonstrate consistent effects of tributyrin on animal performance:
Poultry: Improvements in daily gain, FCR, breast meat yield, and digestibility parameters have been observed when tributyrin is included in the diet. Enhanced villus height in broilers supports nutrient absorption capacity.
Piglets: Supplementation with tributyrin has been associated with improved daily gain, lower FCR, reduced diarrhoea incidence, and increased villus height in the small intestine. Improved digestibility of protein, fat, and metabolic energy has also been reported.
These outcomes are directly linked to improved gut structure and function, rather than short‑term stimulation.
A Practical Solution for Modern Production
Butiphorce 1065 was developed to combine efficacy, safety, and ease of use. Its odour‑free handling and targeted intestinal release make it suitable for practical feed applications in poultry and swine production systems.
In line with NuSana’s approach, the product focuses on measurable performance outcomes, while supporting animal health through well‑understood nutritional mechanisms.
NuSana’s Commitment
NuSana develops feed solutions that are science‑based, reliable, and tailored to real production challenges. Butiphorce 1065 reflects this commitment by translating established nutritional principles into a practical tool for gut health and performance support in poultry and swine.
Interested in Butiphorce 1065 for your poultry or swine programs?
Butiphorce 1065 is designed to support gut integrity and performance through well‑established nutritional mechanisms. If you would like to explore how it can be applied within your feeding strategy, NuSana’s team is ready to support you.


